Theory

• Basic coverage result: random clones of constant length, fixed point
• More sophisticated approach: thinning Poisson processes
  • The number of islands
  • Proportion of coverage
  • # clones in an island
  • The length of an island
• Actual vs apparent islands
  • Variant 1: Partial overlap detection
  • Variant 2: Anchoring random clones
  • Variant 3: Directed mapping
  • Variant 4: Double-end-sequencing