next up previous
Next: Random mating and Up: Coverage of ASP Previous: Coverage of ASP

Strict-recessive model

The ASP possible triangle is covered by the ASP IBD probabilities for a strict-recessive model with general mating type frequencies. That is, for each with , and , we can find a family of mating type frequencies such that are the ASP IBD probabilities for the strict-recessive model with mating type frequencies .

Letting

where c is a positive constant such that , yields .

This illustrates the potentially large impact of non-random mating on the IBD probabilities: under the usual assumptions of random mating and HWE the strict-recessive IBD probabilities are on the Hardy-Weinberg curve, but with general mating type frequencies they cover the entire possible triangle.



Simon Cawley
Tue May 26 19:30:26 PDT 1998